Doctor’s Advice: Can Filler and Biostimulator Be Used Interchangeably? Dr. Saetawut Lertlukpreecha explains clearly, with guidance on choosing the right option for your face.
- Dr. Saetawut Lertlukpreecha

- Aug 6
- 2 min read

Hello, I’m Dr. Saetawut Lertlukpreecha.
One of the most common questions I get at the clinic is:
“Doctor, which is better—Filler or Biostimulator?”
“If I’m already getting fillers, do I also need Biostimulator?”
“Can they replace each other?”
In this article, I’ll explain in a simple and clear way how these two treatments are similar, how they differ, and who they’re suitable for.
What Are Filler and Biostimulator?
Treatment | Primary Function | Result |
Filler (HA) | Instantly restore volume | Immediate results, lasts 8–18 months |
Biostimulator | Stimulates collagen production | Gradual results in 1–3 months, lasts 1–2 years |
How Do They Work Differently?
✅ Filler:
Fills deep hollows (e.g. under eyes, cheeks, chin, temples)
Ideal for those who want immediate results
Allows precise reshaping and contouring of facial features
✅ Biostimulator:
Stimulates your body’s natural collagen production
Best for those who want natural lifting and firmer skin over time
Does not provide instant volume or change facial shape immediately
So, Can They Be Used Interchangeably?
Answer: No, they cannot directly replace one another.
They serve different purposes:
If you have volume loss (e.g. sunken temples, under-eye hollows) → Filler is more appropriate
If you have sagging skin and want a natural lifting effect from within → Biostimulator is the better option
But… Can They Be Used Together?
Yes! And when used together properly, they complement each other very well.
Example of a treatment plan I often use:
Inject Filler in specific hollow areas such as under the eyes or chin
Then use Biostimulator in areas like the cheeks or jawline to stimulate skin tightening
→ The result: a fuller, lifted, and firmer appearance that lasts longer
Doctor’s Recommendations: Who Should Use What?
Facial Concern | Recommended Treatment |
Sunken, flat, or volume-deficient face | Filler |
Thin or slightly sagging skin, no desire to change facial shape | Biostimulator |
Deep tear troughs or nasolabial folds | Filler |
Sagging jawline | Biostimulator |
Want a natural look | Biostimulator or a suitable combination |
Things to Know:
Filler is dissolvable (via Hyaluronidase)
Biostimulator is NOT dissolvable – must be injected by an experienced doctor
Both require a thorough facial structure assessment before treatment
Doctor’s Advice:
“I don’t see Filler and Biostimulator as ‘alternatives,’
but as different tools that can be used together effectively.
The most natural beauty doesn’t come from simply filling—it comes from thoughtful planning with a doctor who understands the skin in depth.”
Summary:
Filler and Biostimulator are not direct substitutes, but can be used together for the best results.
If you want to achieve long-lasting, safe, and natural rejuvenation,
consult a doctor to create a plan tailored to your facial structure and personal goals.






